Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School

Institute of Science and Technology for Brain-inspired Intelligence, Fudan University

  • Transcranial Electric Stimulation (tES) is a noninvasive brain stimulation method with strong potentiality in the field of clinical and neuroscientific research. There are different techniques of tES: Transcranial Direct Current Stimulation (tDCS), transcranial Alternate Current Stimulation (tACS) and transcranial Random Noise Stimulation (tRNS), which have been developed and been rapidly embraced during the last decade. Most recently, the novel approach of Temporally Interfering Electric Stimulation (TIES) offers the potential of selectively stimulating deep brain structures. These tES methods provide a varied set of tools for clinicians and researchers.
  • This workshop is prepared with the help of colleagues from the Berenson-Allen Center for Noninvasive Brain Stimulation (CNBS) at Beth Israel Deaconess Medical Center and Harvard Medical School ( Many experienced researchers are invited to give the presentations to familiarize participants with the fundamentals of the theoretical and practical aspects of tES. The theoretical considerations will include lectures on safety, mechanisms of action, and application in research settings, including the applications in aging, epilepsy, cognitive function, movement disorders, pain and etc. The practical considerations will include sessions on device set-up and parameters for experimental utilization. Regulatory aspects of the use of tES in research, with a particular focus on tDCS, will also be addressed.


  • This workshop will provide from basic to advanced knowledge of tES technologies, as well as its application in basic science and clinical researches to the audience. So researchers in basic neuroscience field and clinical doctors with previous experience in the use of tES and those with no previous experience but with strong interests in tES are both welcomed and can be benefitted by completing the workshop.


6th November,2019

9:00-9:30 Welcome and Introduction of the Workshop and Speakers Emiliano Santarnecchi
9:30-10:30 Past,Present and Future of tES: an Overview on Available Techniques,Opportunities and ChallengesEmiliano Santarnecchi
10:30-10:50Break and Discussion
10:50-11:50UpdateS in tES TechniqueGiulio Ruffini
13:30-14:30tES,spinal code injury and rehabilitation Maria del Mar Cortes
14:30-14:50Break and Discussion
14:50-15:50Demonstration of tDCS(StarStim system)

7th November,2019

9:00-10: 00 tES and psychiatric disordersEmiliano Santarnecchi
10:00-10:20Break and Discussion
10:20-11:20tES in Preclinical ModelsAlexander Rotenberg
11:20-12:00Demonstration of tACS and tRNS
13:00-14:00Aging,Cognitive-Motor Function and tESBrad Manor
14:00-14:20Break and Discussion
14:20-15:20Advanced technologies in tES(modeling,in-house tDCS)Giulio Ruffini
15:20-16:20Demonstration of new technologies
Group photo;
Certificates and souvenir(USB with sides and literatures);



Neuroelectrics® will provide tES system for demonstration, and for best experience, it is important that participants bring their own laptops.

Pre-course questions

  1. How does transcranial electric stimulation (tES) technique modulate the excitability of the brain?
  2. Is there any difference in the mechanisms between tDCS, tACS and tRNS?
  3. What kinds of pathological conditions or disorders can be alleviated by using tES?

Pre-course readings

It is recommended that participant can read the literatures describing the tES techniques, including tDCS, tACS and tRNS. Some suggested publication is as following:

  1. Nitsche MA, Cohen LG, Wassermann EM, Priori A, Lang N, Antal A, Paulus W, Hummel F, Boggio PS, Fregni F, Pascual-Leone A. Transcranial direct current stimulation: state of the art 2008. Brain stimulation. 2008 Jul 1;1(3):206-23.
  2. Antal A, Paulus W. Transcranial alternating current stimulation (tACS). Frontiers in human neuroscience. 2013 Jun 28.
  3. Paulus W. Transcranial electrical stimulation (tES–tDCS; tRNS, tACS) methods. Neuropsychological rehabilitation. 2011 Oct 1;21(5):602-17.


More resources can be found on the website of Center for Non-invasive Brain Stimulation: